The Holy Family of Francis I by Raphael in the Louvre, Paris. Wikipedia cites the historian, Vasari as saying, ‘Raphael’s premature death on Good Friday (April 6, 1520), which was possibly his 37th birthday, was caused by a night of excessive sex with Luti, after which he fell into a fever and, not telling his doctors that this was its cause, was given the wrong cure, which killed him.’ The source footnotes point out that others disagree.

https://en.wikipedia.org/wiki/The_Holy_Family_of_Francis_I_(Raphael)

https://en.wikipedia.org/wiki/Raphael

http://www.louvre.fr/en

https://en.wikipedia.org/wiki/Louvre